W B van den Berg Selected Research

IgG Receptors (Fc gamma RI)

12/2011	Toll-like receptors in rheumatic diseases: are we paying a high price for our defense against bugs?
4/2006	Fc gamma receptor mediated modulation of dendritic cells as a potential strategy in the battle against rheumatoid arthritis.
12/2005	Dendritic cells from patients with rheumatoid arthritis lack the interleukin 13 mediated increase of Fc gamma RII expression, which has clear functional consequences.
11/2005	Dendritic cells, Fc{gamma} receptors, and Toll-like receptors: potential allies in the battle against rheumatoid arthritis.
3/2005	Increased expression of CCL18, CCL19, and CCL17 by dendritic cells from patients with rheumatoid arthritis, and regulation by Fc gamma receptors.
1/2003	Coordinate expression of activating Fc gamma receptors I and III and inhibiting Fc gamma receptor type II in the determination of joint inflammation and cartilage destruction during immune complex-mediated arthritis.
12/2001	Role of activatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and cartilage destruction during experimental antigen-induced arthritis.
4/2000	Role of Fc receptor gamma chain in inflammation and cartilage damage during experimental antigen-induced arthritis.

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W B van den Berg Research Topics

Disease

36	Arthritis (Polyarthritis) 03/2013 - 01/2000
24	Rheumatoid Arthritis 12/2011 - 03/2000
22	Inflammation (Inflammations) 01/2017 - 04/2000
22	Osteoarthritis 01/2017 - 01/2000
16	Experimental Arthritis 03/2013 - 07/2001
10	Osteophyte 01/2016 - 02/2001
10	Necrosis 12/2015 - 11/2000
5	Synovitis 01/2017 - 09/2000
4	Fibrosis (Cirrhosis) 03/2014 - 05/2005
3	Autoimmune Diseases (Autoimmune Disease) 03/2013 - 07/2001
2	Pain (Aches) 03/2015 - 09/2005
2	Rheumatic Diseases (Rheumatism) 12/2011 - 05/2005
2	Hyperplasia 02/2001 - 02/2001
1	Systemic Scleroderma (Systemic Sclerosis) 12/2011
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 12/2011
1	Hypoxia (Hypoxemia) 04/2011
1	Disease Progression 03/2011
1	Atherosclerosis 10/2009
1	Infections 09/2009

Drug/Important Bio-Agent (IBA)

21	CytokinesIBA 01/2017 - 01/2000
15	Interleukin-1 (Interleukin 1)IBA 01/2017 - 11/2000
12	Transforming Growth Factor beta (TGF-beta)IBA 01/2013 - 01/2000
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2009 - 01/2001
9	Matrix Metalloproteinases (MMPs)IBA 01/2016 - 04/2000
9	Collagen Type II (Type II Collagen)IBA 09/2008 - 03/2000
8	Proteins (Proteins, Gene)FDA Link 01/2017 - 03/2000
8	IgG Receptors (Fc gamma RI)IBA 12/2011 - 04/2000
7	Antigen-Antibody Complex (Immune Complex)IBA 12/2011 - 11/2001
7	AntigensIBA 09/2011 - 04/2000
6	InterleukinsIBA 12/2015 - 12/2005
6	Toll-Like Receptors (Toll-Like Receptor)IBA 03/2013 - 08/2005
6	Interleukin-17 (Interleukin 17)IBA 10/2009 - 07/2001
5	Collagenases (Collagenase)FDA Link 01/2017 - 11/2006
5	Metalloproteases (Metalloproteinases)IBA 04/2011 - 12/2001
5	Proteoglycans (Proteoglycan)IBA 12/2008 - 12/2001
4	Liposomes (Liposome)IBA 09/2011 - 09/2000
4	Interleukin-18 (Interleukin 18)IBA 01/2010 - 11/2001
4	Interleukin-6 (Interleukin 6)IBA 09/2008 - 07/2001
4	Interleukin-4 (Interleukin 4)IBA 12/2007 - 02/2001
3	AlarminsIBA 01/2016 - 08/2014
3	CollagenIBA 03/2014 - 12/2007
3	Interleukin-10 (Interleukin 10)IBA 09/2008 - 11/2001
3	ZymosanIBA 05/2006 - 03/2000
3	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 04/2006 - 06/2002
3	Interleukin-1beta (Interleukin 1 beta)IBA 09/2005 - 07/2001
2	oxidized low density lipoproteinIBA 01/2017 - 05/2016
2	Bone Morphogenetic Protein 2IBA 06/2015 - 12/2007
2	safranine T (safranin)IBA 06/2015 - 12/2001
2	Transforming Growth Factors (Transforming Growth Factor)IBA 03/2014 - 04/2011
2	prednisolone phosphate FDA LinkGeneric 09/2011 - 04/2004
2	GlucocorticoidsIBA 09/2011 - 04/2004
2	Peptide Hydrolases (Proteases)FDA Link 09/2011 - 03/2002
2	Biological ProductsIBA 01/2010 - 12/2007
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 05/2009 - 04/2007
2	Messenger RNA (mRNA)IBA 12/2008 - 07/2001
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 09/2008 - 09/2000
2	Therapeutic UsesIBA 09/2008 - 04/2007
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 07/2005 - 06/2002
2	Interleukin-1 Receptor Accessory ProteinIBA 07/2005 - 10/2003
2	AntibodiesIBA 10/2003 - 03/2002
2	Muramidase (Lysozyme)IBA 01/2003 - 03/2002
1	RNA (Ribonucleic Acid)IBA 01/2017
1	CholesterolIBA 05/2016
1	Apolipoproteins E (ApoE)IBA 05/2016
1	C-Reactive ProteinIBA 01/2016
1	Cartilage Oligomeric Matrix ProteinIBA 01/2016
1	peptide VDIPENIBA 01/2016
1	paquinimodIBA 12/2015
1	Nerve Growth Factor (NGF)IBA 03/2015
1	LigandsIBA 03/2013
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 03/2013
1	growth arrest-specific protein 6IBA 03/2013
1	Protein SIBA 03/2013
1	2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine (Lysyl Hydroxylase)IBA 01/2013
1	pyridinolineIBA 01/2013
1	Transcription Factors (Transcription Factor)IBA 04/2011
1	Phospholipases (Phospholipase)IBA 03/2011
1	DNA (Deoxyribonucleic Acid)IBA 03/2011
1	EnzymesIBA 03/2011
1	Small Interfering RNA (siRNA)IBA 03/2011
1	Interleukin-18 ReceptorsIBA 01/2010
1	Interleukin-17 ReceptorsIBA 10/2009
1	Class A Scavenger ReceptorsIBA 10/2009
1	Interleukin-12 (IL 12)IBA 09/2009
1	Interferon Type IIBA 09/2009
1	Interferon-alpha (Interferon Alfa)IBA 09/2009
1	ThrombospondinsIBA 12/2008
1	aggrecanaseIBA 12/2008
1	DisintegrinsIBA 12/2008
1	Interleukin-2 (IL2)IBA 09/2008
1	Prostaglandins EIBA 09/2008
1	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 12/2007
1	Toll-Like Receptor 4IBA 03/2007
1	Insulin-Like PeptidesIBA 05/2006
1	Insulin-Like Growth Factor I (IGF-1)IBA 05/2006
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2006
1	Interleukin-13IBA 12/2005

Therapy/Procedure

5	Therapeutics 11/2006 - 01/2001
3	Injections 01/2017 - 01/2000
3	Intra-Articular Injections 05/2009 - 01/2000